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    • M. tuberculosis H37Rv: Rv0009 - iron-regulated peptidyl-prolyl-cis-trans-isomerase A ppiA

    << Previous Gene on Contig (Rv0008c ) Next Gene on Contig (Rv0010c ) >>
    VIEWS & TOOLS
    expression
    regulation
    genome analysis
    Curated Citations
    7
    Orthologs
    30
    Reactions
    1
    Pathways
    0
    COG Annotation
    1
    GO Annotations
    0
    Protein Structures
    1
    Gene Profiles
    32
    Expression Conditions
    6
    SNPs
    5
    Operons
    1
    Epitopes
    0
    Legend
    Protein Domains
    Gene Id : 7000000635248034
    Gene Info Collapse
    Locus Rv0009
    Gene Symbol ppiA
    Synonyms  
    Gene Name iron-regulated peptidyl-prolyl-cis-trans-isomerase A ppiA  
    Closely Related Orthologs peptidylprolyl isomerase ?
    Location M. tuberculosis H37Rv: Chromosome 1: 12468-13016 +
    Length Gene: 549 nt
    Protein: 182 aa
    External Links TubercuList ?
    TBSGC Protein Structure Information ?
    TARGET Gene Information ?
    Proteome 2D-PAGE Database - Search ?
    Search Google Scholar ?
    Protein Domains View Gene Neighborhood with Protein Domains and Polymorphisms
    Diversity Graph Collapse
     
    View Multiple Alignment of Diversity Strains for Rv0009
    Show All SNPs in Diversity Strains for Rv0009
    Gene Expression Collapse
    Gene Expression Data
    Gene Profiles ?
    Samples And Conditions ?
    Genes with Correlated Expression
    Scatterplot of Gene Expression
    Protein Information Collapse
    Protein Structure View Protein Structure
    Functional Annotations Collapse
    Reactions EC# 5.2.1.8 - peptidylproline (ω = 180) = peptidylproline (ω = 0)
    COG Annotations COG:O ? Posttranslational modification, protein turnover, chaperones
    Operons ppiA-ppiA ? Operon
    TraSH Essentiality
    (see Sassetti et al., 2003)    		 Not Essential
    Tools Collapse
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    Curated Publications Collapse
    D. Mitra, S. Mukherjee et al. Cyclosporin A binding to Mycobacterium tuberculosis peptidyl-prolyl cis-trans isomerase A--investigation by CD, FTIR and fluorescence spectroscopy. FEBS Lett. 2006 PMID:17141764
    promoted robriley 2009-01-06
    LM. Henriksson, P. Johansson et al. X-ray structure of peptidyl-prolyl cis-trans isomerase A from Mycobacterium tuberculosis. Eur. J. Biochem. 2004 PMID:15479239
    promoted robriley 2009-02-05
    MI. Voskuil, D. Schnappinger et al. Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program. J. Exp. Med. 2003 PMID:12953092
    promoted psisk 2009-06-10
    HI. Boshoff, TG. Myers et al. The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action. J. Biol. Chem. 2004 PMID:15247240
    promoted psisk 2009-06-10
    GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002 PMID:12065475
    promoted psisk 2009-06-10
    Q. Gao, K. Kripke et al. Comparative expression studies of a complex phenotype: cord formation in Mycobacterium tuberculosis. Tuberculosis (Edinb) 2004 PMID:15207488
    promoted psisk 2009-06-10
    Q. Gao, KE. Kripke et al. Gene expression diversity among Mycobacterium tuberculosis clinical isolates. Microbiology (Reading, Engl.) 2005 PMID:15632420
    promoted psisk 2009-06-10
    Publications Awaiting Curatorial Review Collapse
    R. Manganelli, MI. Voskuil et al.The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages.Mol. Microbiol.2001
    curated sgi 2009-07-27
    TR. Rustad, MI. Harrell et al.The enduring hypoxic response of Mycobacterium tuberculosis.PLoS ONE2008
    curated sgi 2009-07-27
    X. Pang, P. Vu et al.Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant of Mycobacterium tuberculosis.Microbiology (Reading, Engl.)2007
    curated sgi 2009-07-27
    MI. Voskuil, KC. Visconti et al.Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy.Tuberculosis (Edinburgh, Scotland)2004
    curated sgi 2009-07-28
    G. Rehren, S. Walters et al.Differential gene expression between Mycobacterium bovis and Mycobacterium tuberculosis.Tuberculosis (Edinb)2007
    curated sgi 2009-07-28
    RP. Morris, L. Nguyen et al.Ancestral antibiotic resistance in Mycobacterium tuberculosis.Proc. Natl. Acad. Sci. U.S.A.2005
    curated sgi 2009-07-28
    HD. Park, KM. Guinn et al.Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis.Mol. Microbiol.2003
    curated sgi 2009-07-28
    DR. Sherman, M. Voskuil et al.Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin.Proc. Natl. Acad. Sci. U.S.A.2001
    curated sgi 2009-07-28
    N. Andreu & I. GibertCell population heterogeneity in Mycobacterium tuberculosis H37Rv.Tuberculosis (Edinb)2008
    curated sgi 2009-07-28
    R. Manganelli, MI. Voskuil et al. Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression. Mol. Microbiol. 2002 PMID:12123450
    curated sgi 2009-07-30
    A. Deenadayalan, JC. Sundaramurthi et al. Immunological and proteomic analysis of preparative isoelectric focusing separated culture filtrate antigens of Mycobacterium tuberculosis. Exp. Mol. Pathol. 2010 PMID:19944092
    active annot 2010-05-20
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    Genomic Sequence