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  • Rv2346c - Esat-6 like protein esxO


    Protein Domains

    Gene Information
    LocusRv2346c
    SymbolesxO
    Gene NameEsat-6 like protein esxO
    Location2625888 - 2626172 (-)
    SpeciesMycobacterium tuberculosis H37Rv complete genome.
    LengthGene:285 bp
    Protein:95 aa
    External LinksTuberculist
    Target Gene Information
    String Protein-Protein Interactions
    STITCH Chemical-Protein Interactions
    Search Google Scholar
    Orthologs
    Orthogroup Number11442
    Related GenesMT2411 MT2420
    Transcriptional Regulation
    Operons View gene in operon browser
    Regulatory Network
    Search for regulators of Rv2346c
    Gene Expression Gene Profiles
    Samples and Conditions
    Expression Correlation Genes with Correlated Expression
    Scatterplot of Gene Expression

    Sequence
    Proteins
    Genomic Sequence
    Community Annotations Pending Curatorial Review
    FieldValueStatusCreatorDate
    InteractionSignaling Rv2347cactivejhum4u20062012-10-05
    Co-Occurrence (Functional Linkage)
    KL. Lightbody, D. Ilghari et al. Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. J. Biol. Chem. 2008
    InteractionSignaling Rv2347cactivejhum4u20062012-10-05
    Co-Occurrence (Functional Linkage)
    PA. Champion, SA. Stanley et al. C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science 2006
    InteractionSignaling Rv2347cactivejhum4u20062012-10-05
    Co-Occurrence (Functional Linkage)
    Y. Feng,X. Yang,Z. Liu,Y. Liu,B. Su,Y. Ding,L. Qin,H. Yang,R. Zheng,Z. Hu Continuous treatment with recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein activated human monocyte while deactivated LPS-stimulated macrophage. Biochem. Biophys. Res. Commun. 2008
    InteractionSignaling Rv2347cactivejhum4u20062012-10-05
    Co-Occurrence (Functional Linkage)
    KL. Lightbody, D. Ilghari et al. Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. J. Biol. Chem. 2008
    InteractionSignaling Rv2347cactivejhum4u20062012-10-05
    Co-Occurrence (Functional Linkage)
    PA. Champion, SA. Stanley et al. C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science 2006
    InteractionSignaling Rv2347cactivejhum4u20062012-10-05
    Co-Occurrence (Functional Linkage)
    Y. Feng,X. Yang,Z. Liu,Y. Liu,B. Su,Y. Ding,L. Qin,H. Yang,R. Zheng,Z. Hu Continuous treatment with recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein activated human monocyte while deactivated LPS-stimulated macrophage. Biochem. Biophys. Res. Commun. 2008
    InteractionRegulatedBy Rv1221activeyamir.moreno2012-10-05
    Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
    R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
    InteractionSignaling Rv2347cactivejhum4u20062012-10-03
    Co-Occurrence (Functional Linkage)
    KL. Lightbody, D. Ilghari et al. Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. J. Biol. Chem. 2008
    InteractionSignaling Rv2347cactivejhum4u20062012-10-03
    Co-Occurrence (Functional Linkage)
    PA. Champion, SA. Stanley et al. C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science 2006
    InteractionSignaling Rv2347cactivejhum4u20062012-10-03
    Co-Occurrence (Functional Linkage)
    Y. Feng,X. Yang,Z. Liu,Y. Liu,B. Su,Y. Ding,L. Qin,H. Yang,R. Zheng,Z. Hu Continuous treatment with recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein activated human monocyte while deactivated LPS-stimulated macrophage. Biochem. Biophys. Res. Commun. 2008
    InteractionSignaling Rv2347cactivejhum4u20062012-10-03
    Co-Occurrence (Functional Linkage)
    KL. Lightbody, D. Ilghari et al. Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. J. Biol. Chem. 2008
    InteractionSignaling Rv2347cactivejhum4u20062012-10-03
    Co-Occurrence (Functional Linkage)
    PA. Champion, SA. Stanley et al. C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science 2006
    InteractionSignaling Rv2347cactivejhum4u20062012-10-03
    Co-Occurrence (Functional Linkage)
    Y. Feng,X. Yang,Z. Liu,Y. Liu,B. Su,Y. Ding,L. Qin,H. Yang,R. Zheng,Z. Hu Continuous treatment with recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein activated human monocyte while deactivated LPS-stimulated macrophage. Biochem. Biophys. Res. Commun. 2008