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  • Rv2875 - major secreted immunogenic protein mpt70


    Protein Domains

    Gene Information
    LocusRv2875
    Symbolmpt70
    Gene Namemajor secreted immunogenic protein mpt70
    Location3187030 - 3187611 (+)
    SpeciesMycobacterium tuberculosis H37Rv complete genome.
    LengthGene:582 bp
    Protein:194 aa
    External LinksTuberculist
    Target Gene Information
    String Protein-Protein Interactions
    STITCH Chemical-Protein Interactions
    Search Google Scholar
    Orthologs
    Orthogroup Number13869
    Related GenesCE0063 Mkms_2086 Mkms_2087 Mkms_4153 Mmcs_2040 Mmcs_2041 Mmcs_4077 MSMEG_5196 MT2940 MT2943 Mvan_2258 Mvan_2259 Mvan_4586 Rv2873
    Transcriptional Regulation
    Operons View gene in operon browser
    Regulatory Network
    Search for regulators of Rv2875
    Gene Expression Gene Profiles
    Samples and Conditions
    Expression Correlation Genes with Correlated Expression
    Scatterplot of Gene Expression

    Sequence
    Proteins
    Genomic Sequence
    Community Annotations Pending Curatorial Review
    FieldValueStatusCreatorDate
    InteractionRegulatory Rv0445cactiveshahanup862012-10-05
    Affinity purification (Physical interaction)
    authors,S. Rodrigue,J. Brodeur,PE. Jacques,AL. Gervais,R. Brzezinski,L. Gaudreau Identification of mycobacterial sigma factor binding sites by chromatin immunoprecipitation assays. J. Bacteriol. 2007
    InteractionRegulatory Rv0445cactiveshahanup862012-10-05
    Affinity purification (Physical interaction)
    F. Veyrier, B. Saïd-Salim et al. Evolution of the mycobacterial SigK regulon. J. Bacteriol. 2008
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,K. Miura,S. Nagai,M. Kinomoto,S. Haga,T. Tokunaga Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70. Infect. Immun. 1983
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,K. Miura,S. Nagai,M. Kinomoto,S. Haga,T. Tokunaga Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70. Infect. Immun. 1983
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,K. Miura,S. Nagai,M. Kinomoto,S. Haga,T. Tokunaga Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70. Infect. Immun. 1983
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,KA. Lightbody,RM. Girvin,DP. Mackie,SD. Neill,JM. Pollock T-cell recognition of mycobacterial proteins MPB70 and MPB64 in cattle immunized with antigen and infected with Mycobacterium bovis. Scand. J. Immunol. 1998
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,KA. Lightbody,RM. Girvin,DP. Mackie,SD. Neill,JM. Pollock T-cell recognition of mycobacterial proteins MPB70 and MPB64 in cattle immunized with antigen and infected with Mycobacterium bovis. Scand. J. Immunol. 1998
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,KA. Lightbody,RM. Girvin,DP. Mackie,SD. Neill,JM. Pollock T-cell recognition of mycobacterial proteins MPB70 and MPB64 in cattle immunized with antigen and infected with Mycobacterium bovis. Scand. J. Immunol. 1998
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,JM. Pollock,AJ. Douglas,DP. Mackie,SD. Neill Identification of bovine T-cell epitopes for three Mycobacterium bovis antigens: MPB70, 19,000 MW and MPB57. Immunology 1994
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,JM. Pollock,AJ. Douglas,DP. Mackie,SD. Neill Identification of bovine T-cell epitopes for three Mycobacterium bovis antigens: MPB70, 19,000 MW and MPB57. Immunology 1994
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,JM. Pollock,AJ. Douglas,DP. Mackie,SD. Neill Identification of bovine T-cell epitopes for three Mycobacterium bovis antigens: MPB70, 19,000 MW and MPB57. Immunology 1994
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,HG. Wiker,KP. Lyashchenko,AM. Aksoy,KA. Lightbody,JM. Pollock,SV. Komissarenko,SO. Bobrovnik,IN. Kolesnikova,LO. Mykhalsky,ML. Gennaro,M. Harboe Immunochemical characterization of the MPB70/80 and MPB83 proteins of Mycobacterium bovis. Infect. Immun. 1998
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,HG. Wiker,KP. Lyashchenko,AM. Aksoy,KA. Lightbody,JM. Pollock,SV. Komissarenko,SO. Bobrovnik,IN. Kolesnikova,LO. Mykhalsky,ML. Gennaro,M. Harboe Immunochemical characterization of the MPB70/80 and MPB83 proteins of Mycobacterium bovis. Infect. Immun. 1998
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,HG. Wiker,KP. Lyashchenko,AM. Aksoy,KA. Lightbody,JM. Pollock,SV. Komissarenko,SO. Bobrovnik,IN. Kolesnikova,LO. Mykhalsky,ML. Gennaro,M. Harboe Immunochemical characterization of the MPB70/80 and MPB83 proteins of Mycobacterium bovis. Infect. Immun. 1998
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    W. Vosloo, P. Tippoo et al. Characterisation of a lipoprotein in Mycobacterium bovis (BCG) with sequence similarity to the secreted protein MPB70. Gene 1997
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    W. Vosloo, P. Tippoo et al. Characterisation of a lipoprotein in Mycobacterium bovis (BCG) with sequence similarity to the secreted protein MPB70. Gene 1997
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    W. Vosloo, P. Tippoo et al. Characterisation of a lipoprotein in Mycobacterium bovis (BCG) with sequence similarity to the secreted protein MPB70. Gene 1997
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    M. Harboe, HG. Wiker et al. MPB70 and MPB83 as indicators of protein localization in mycobacterial cells. Infect. Immun. 1998
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    M. Harboe, HG. Wiker et al. MPB70 and MPB83 as indicators of protein localization in mycobacterial cells. Infect. Immun. 1998
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    M. Harboe, HG. Wiker et al. MPB70 and MPB83 as indicators of protein localization in mycobacterial cells. Infect. Immun. 1998
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,M. Harboe,S. Nagai MPB70, a unique antigen of Mycobacterium bovis BCG. Am. Rev. Respir. Dis. 1984
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,M. Harboe,S. Nagai MPB70, a unique antigen of Mycobacterium bovis BCG. Am. Rev. Respir. Dis. 1984
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,M. Harboe,S. Nagai MPB70, a unique antigen of Mycobacterium bovis BCG. Am. Rev. Respir. Dis. 1984
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,K. Terasaka,R. Yamaguchi,K. Matsuo,A. Yamazaki,S. Nagai,T. Yamada Complete nucleotide sequence of immunogenic protein MPB70 from Mycobacterium bovis BCG. FEMS Microbiol. Lett. 1989
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,K. Terasaka,R. Yamaguchi,K. Matsuo,A. Yamazaki,S. Nagai,T. Yamada Complete nucleotide sequence of immunogenic protein MPB70 from Mycobacterium bovis BCG. FEMS Microbiol. Lett. 1989
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,K. Terasaka,R. Yamaguchi,K. Matsuo,A. Yamazaki,S. Nagai,T. Yamada Complete nucleotide sequence of immunogenic protein MPB70 from Mycobacterium bovis BCG. FEMS Microbiol. Lett. 1989
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,MD. Carr,MJ. Bloemink,E. Dentten,AO. Whelan,SV. Gordon,G. Kelly,TA. Frenkiel,RG. Hewinson,RA. Williamson Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease. J. Biol. Chem. 2003
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,MD. Carr,MJ. Bloemink,E. Dentten,AO. Whelan,SV. Gordon,G. Kelly,TA. Frenkiel,RG. Hewinson,RA. Williamson Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease. J. Biol. Chem. 2003
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    authors,MD. Carr,MJ. Bloemink,E. Dentten,AO. Whelan,SV. Gordon,G. Kelly,TA. Frenkiel,RG. Hewinson,RA. Williamson Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease. J. Biol. Chem. 2003
    InteractionPhysicalInteraction Rv2872activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    MD. Juárez, A. Torres et al. Characterization of the Mycobacterium tuberculosis region containing the mpt83 and mpt70 genes. FEMS Microbiol. Lett. 2001
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    MD. Juárez, A. Torres et al. Characterization of the Mycobacterium tuberculosis region containing the mpt83 and mpt70 genes. FEMS Microbiol. Lett. 2001
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    MD. Juárez, A. Torres et al. Characterization of the Mycobacterium tuberculosis region containing the mpt83 and mpt70 genes. FEMS Microbiol. Lett. 2001
    InteractionPhysicalInteraction Rv2874activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    MD. Juárez, A. Torres et al. Characterization of the Mycobacterium tuberculosis region containing the mpt83 and mpt70 genes. FEMS Microbiol. Lett. 2001
    InteractionPhysicalInteraction Rv2873activepriti.priety2012-10-05
    Gene Neighborhood (Functional linkage)
    MD. Juárez, A. Torres et al. Characterization of the Mycobacterium tuberculosis region containing the mpt83 and mpt70 genes. FEMS Microbiol. Lett. 2001