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  • Rv0589 - MCE-family protein mce2A


    Protein Domains

    Gene Information
    LocusRv0589
    Symbolmce2A
    Gene NameMCE-family protein mce2A
    Location686821 - 688035 (+)
    SpeciesMycobacterium tuberculosis H37Rv complete genome.
    LengthGene:1215 bp
    Protein:405 aa
    External LinksTuberculist
    Target Gene Information
    String Protein-Protein Interactions
    STITCH Chemical-Protein Interactions
    Search Google Scholar
    Orthologs
    Orthogroup Number21310
    Related GenesMAP4084 MAV_4551 MT0618
    Transcriptional Regulation
    Operons View gene in operon browser
    Regulatory Network
    Search for regulators of Rv0589
    Gene Expression Gene Profiles
    Samples and Conditions
    Expression Correlation Genes with Correlated Expression
    Scatterplot of Gene Expression

    Sequence
    Proteins
    Genomic Sequence
    Community Annotations Pending Curatorial Review
    FieldValueStatusCreatorDate
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,M. Alonso-Hearn,TM. Eckstein,S. Sommer,LE. Bermudez A Mycobacterium avium subsp. paratuberculosis LuxR regulates cell envelope and virulence. Innate Immun 2010
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    Y. Haile, DA. Caugant et al. Mycobacterium tuberculosis mammalian cell entry operon (mce) homologs in Mycobacterium other than tuberculosis (MOTT). FEMS Immunol. Med. Microbiol. 2002
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    O. Marjanovic,T. Miyata,A. Goodridge,LV. Kendall,LW. Riley Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis (Edinb) 2010
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    AK. Das, D. Mitra et al. Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 2003
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    AK. Das, D. Mitra et al. Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 2003
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    AK. Das, D. Mitra et al. Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 2003
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    AK. Das, D. Mitra et al. Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 2003
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    AK. Das, D. Mitra et al. Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 2003
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    AK. Das, D. Mitra et al. Predicted molecular structure of the mammalian cell entry protein Mce1A of Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 2003
    InteractionOperon Rv0594activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
    InteractionOperon Rv0593activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
    InteractionOperon Rv0592activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
    InteractionOperon Rv0591activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
    InteractionOperon Rv0590Aactivekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
    InteractionOperon Rv0590activekholia.trupti2012-10-05
    Co-expression (Functional linkage)
    D. Mitra, B. Saha et al. Correlating sequential homology of Mce1A, Mce2A, Mce3A and Mce4A with their possible functions in mammalian cell entry of Mycobacterium tuberculosis performing homology modeling. Tuberculosis (Edinburgh, Scotland) null
    InteractionRegulatory Rv0586activesourish102012-10-05
    Physical Interaction
    MD. Santangelo, F. Blanco et al. Mce2R from Mycobacterium tuberculosis represses the expression of the mce2 operon repressor from M. tuberculosis. Tuberculosis (Edinburgh, Scotland) 2008
    InteractionRegulatory Rv0586activesourish102012-10-05
    Physical Interaction
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionRegulatory Rv0586activeahal47892012-10-05
    Physical Interaction
    MD. Santangelo, F. Blanco et al. Mce2R from Mycobacterium tuberculosis represses the expression of the mce2 operon repressor from M. tuberculosis. Tuberculosis (Edinburgh, Scotland) 2008
    InteractionRegulatory Rv0586activeahal47892012-10-05
    Physical Interaction
    authors,A. Kumar,M. Bose,V. Brahmachari Analysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. Infect. Immun. 2003
    InteractionRegulatedBy Rv0586activeyamir.moreno2012-10-05
    LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.).
    MD. Santangelo, F. Blanco et al. Mce2R from Mycobacterium tuberculosis represses the expression of the mce2 operon repressor from M. tuberculosis. Tuberculosis (Edinburgh, Scotland) 2008