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  • Rv2031c - heat shock protein hspX


    Protein Domains

    Gene Information
    LocusRv2031c
    SymbolhspX
    Gene Nameheat shock protein hspX
    Location2278498 - 2278932 (-)
    SpeciesMycobacterium tuberculosis H37Rv complete genome.
    LengthGene:435 bp
    Protein:145 aa
    External LinksTuberculist
    Target Gene Information
    String Protein-Protein Interactions
    STITCH Chemical-Protein Interactions
    Search Google Scholar
    Orthologs
    Orthogroup Number29267
    Related GenesAcel_0160 Mkms_1098 MSMEG_3932 MT2090 Mvan_1374 nfa8400 PPA0737
    Transcriptional Regulation
    Operons View gene in operon browser
    Regulatory Network
    Search for regulators of Rv2031c
    Gene Expression Gene Profiles
    Samples and Conditions
    Expression Correlation Genes with Correlated Expression
    Scatterplot of Gene Expression

    Sequence
    Proteins
    Genomic Sequence
    Community Annotations Pending Curatorial Review
    FieldValueStatusCreatorDate
    InteractionRegulatory Rv2069activeashwinigbhat2012-10-05
    Co-expression (Functional linkage)
    R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
    InteractionRegulatory Rv2069activepriti.priety2012-10-05
    Co-expression (Functional linkage)
    R. Sun, PJ. Converse et al. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol. Microbiol. 2004
    InteractionRegulatory Rv2034activepriti.priety2012-10-05
    Bacterial one-hybrid system
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatory Rv2032activepriti.priety2012-10-05
    Spectrophotometric analysis
    A. Purkayastha, LA. McCue et al. Identification of a Mycobacterium tuberculosis putative classical nitroreductase gene whose expression is coregulated with that of the acr aene within macrophages, in standing versus shaking cultures, and under low oxygen conditions. Infect. Immun. 2002
    InteractionSignaling Rv3133cactivepriti.priety2012-10-05
    affinity purification
    A. Demissie, EM. Leyten et al. Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin. Vaccine Immunol. 2006
    InteractionSignaling Rv3133cactivepriti.priety2012-10-05
    affinity purification
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatory Rv2007cactiveprabhakarsmail2012-10-05
    co-expression(Functional linkage)
    A. Kumar,JC. Toledo,RP. Patel,JR. Lancaster,AJ. Steyn Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor. Proc. Natl. Acad. Sci. U.S.A. 2007
    InteractionRegulatory Rv2007cactiveakankshajain.212012-10-05
    co-expression(Functional linkage)
    A. Kumar,JC. Toledo,RP. Patel,JR. Lancaster,AJ. Steyn Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor. Proc. Natl. Acad. Sci. U.S.A. 2007
    InteractionRegulatory Rv1997activejgalag2012-10-05

    authors,H. Ohno,G. Zhu,VP. Mohan,D. Chu,S. Kohno,WR. Jacobs,J. Chan The effects of reactive nitrogen intermediates on gene expression in Mycobacterium tuberculosis. Cell. Microbiol. 2003
    InteractionRegulatory Rv1997activejgalag2012-10-05

    D. Agranoff & S. Krishna Metal ion transport and regulation in Mycobacterium tuberculosis. Front. Biosci. 2004
    InteractionRegulatory Rv1997activejgalag2012-10-05

    MA. Florczyk, LA. McCue et al. A family of acr-coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for expression. Infect. Immun. 2003
    InteractionRegulatory Rv1996activepriyadarshinipriyanka20012012-10-05
    Co-expression (Functional linkage)
    authors,SM. Hingley-Wilson,KE. Lougheed,K. Ferguson,S. Leiva,HD. Williams Individual Mycobacterium tuberculosis universal stress protein homologues are dispensable in vitro. Tuberculosis (Edinb) 2010
    InteractionRegulatory Rv1996activepriyadarshinipriyanka20012012-10-05
    Co-expression (Functional linkage)
    MA. Florczyk, LA. McCue et al. A family of acr-coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for expression. Infect. Immun. 2003
    InteractionRegulatory Rv0757activesinghpankaj21162012-10-05
    Structural Analysis
    J. Gonzalo-Asensio, S. Mostowy et al. PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. PLoS ONE 2008
    InteractionRegulatory Rv0757activesinghpankaj21162012-10-05
    Spectrophotometric
    J. Gonzalo-Asensio, S. Mostowy et al. PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. PLoS ONE 2008
    InteractionRegulatedBy Rv0348activeyamir.moreno2012-10-05
    Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
    B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
    InteractionRegulatedBy Rv3681cactiveyamir.moreno2012-10-05
    One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatedBy Rv3678cactiveyamir.moreno2012-10-05
    One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatedBy Rv3416activeyamir.moreno2012-10-05
    One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatedBy Rv3133cactiveyamir.moreno2012-10-05
    One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatedBy Rv2034activeyamir.moreno2012-10-05
    One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatedBy Rv0445cactiveyamir.moreno2012-10-05
    One hybrid reporter system. Physical binding of the regulator to the regulated promoter proved by using electrophoretic mobility shift assay. .
    M. Guo, H. Feng et al. Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system. Genome Res. 2009
    InteractionRegulatedBy Rv3133cactiveyamir.moreno2012-10-05
    Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
    G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
    InteractionRegulatedBy Rv2069activeyamir.moreno2012-10-05
    Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
    G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008